You may get an error are Yum attempting to Update or when you installing Packages, 404 Error Returned. 


#  yum update

Loaded plugins: fastestmirror
Loading mirror speeds from cached hostfile
 * base: mirror.chpc.utah.edu
 * epel: mirror.chpc.utah.edu
 * extras: mirrors.usc.edu
 * updates: mirrors.cat.pdx.edu
http://mirror.chpc.utah.edu/pub/centos/6.6/os/x86_64/repodata/repomd.xml: [Errno 14] PYCURL ERROR 22 - "The requested URL returned error: 404 Not Found"
Trying other mirror.
http://linux.mirrors.es.net/centos/6.6/os/x86_64/repodata/repomd.xml: [Errno 14] PYCURL ERROR 22 - "The requested URL returned error: 404 Not Found"


Verify that channel is not listed and then add the same channel again by :-


# yum repolist

# yum clean all


If the above commands could not solve an error, let us run a few more commands that will make sure you have a clean and up to date version of yum:


# yum check 

# yum upgrade